A novel, low temperature method for the preparation of beta-TCP/HAP biphasic nanostructured ceramic scaffold from natural cancellous bone

作者：Emadi R; Esfahani S I Roohani; Tavangarian F^*

来源：Materials Letters, 2010, 64(8): 993-996.

DOI：10.1016/j.matlet.2010.01.085

• Ceramics
• X-ray techniques
• Biphasic calcium phosphate
• Hydroxyapatite
• beta-tricalcium phosphate
• Nanostructures

In this study, a novel method was used to synthesize beta-TCP/HAP biphasic ceramic scaffold from natural cancellous bone. Bovine bone was calcined to remove the organic content. The remaining material was then soaked in P(2)O(5) solution for different periods. P ions were doped into cancellous bone and reacted with hydroxyapatite (HAP) to produce beta-tricalcium phosphate (beta-TCP) at room temperature without any subsequent high-temperature heat treatment. By increasing the soaking time, the crystalline phase composition of the calcined bone gradually changed from HAP into a HAP/beta-TCP biphasic structure with different HAP/TCP ratios. The crystallite size of HAP and beta-TCP was smaller than 100 nm.

• 出版日期2010-4-30