A simple, novel and convenient method for the synthesis of 1-aminophosphinic acids: synthesis of a novel C-2-symmetric phosphinic acid pseudodipeptide

作者：Kaboudin Babak^*; Saadati Fariba

来源：Tetrahedron Letters, 2009, 50(13): 1450-1452.

DOI：10.1016/j.tetlet.2009.01.055

A simple, efficient and novel method has been developed for the synthesis of 1-aminophosphinic acids from simple starting materials. Treatment of aromatic aldehydes with ammonia and hypophosphorus acid gives novel C-2-symmetric 1-aminoarylmethylphosphinic acids. The synthesis of novel C-2-symmetric phosphinic acid pseudodipeptides is also discussed.

• 出版日期2009-4-1