New chiral 1,2-aminoalcohols derived from biomass and their application in diethyl zinc additions

作者：Zanardi Maria M; Botta Maria C; Suarez Alejandra G^*

来源：Tetrahedron Letters, 2014, 55(42): 5832-5835.

DOI：10.1016/j.tetlet.2014.08.124

• Levoglucosenone
• 1,2-Aminoalcohols
• Chiral ligands
• Asymmetric induction

A convenient procedure for the preparation of chiral 1,2-aminoalcohols starting from levoglucosenone, a biomass derivative, is described. The 1,2-aminoalcohols, bearing primary, secondary, and tertiary amino groups, were tested as chiral catalysts in the asymmetric addition of diethyl zinc to benzaldehyde.

• 出版日期2014-10-15