MULTIDRUG RESISTANT AND EXTENDED SPECTRUM beta-LACTAMASE PRODUCING SALMONELLA ENTERICA ISOLATED FROM FOOD ANIMALS IN PHATTHALUNG, THAILAND

作者：Lertworapreecha Monthon^*; Noomee Sirilak; Sutthimusik Suparat; Utarapichat Bussakorn; Tontikapong Kumchai

来源：Southeast Asian Journal of Tropical Medicine and Public Health, 2016, 47(6): 1257-1269.

• Salmonella enterica
• animal feces
• animal meat
• extended spectrum beta-lactamase (ESBL)
• Thailand

This study investigated antimicrobial resistance profiles and genes of beta-lactamase-producing Salmonella enterica, isolates from animal feces and meat samples at small-scale rural farms in Phatthalung Province, Thailand. Of 40 isolates from swine feces 50%, 47%, 17%, 17%, and 15% were resistant to ampicillin, streptomycin, nalidixic acid, tetracycline, and chloramphenicol, respectively; of 29 isolates from chicken feces 33%, 27%, 7%, and 3% were resistant to streptomycin, nalidixic acid, tetracycline, and ampicillin, respectively; and of 6 isolates from cattle feces 67% were resistant to sulfamethoxazole and tetracycline, and 33% resistant to ampicillin, nalidixic acid and streptomycin. Of the 23 isolates from chicken meat 96%, 96%, 78%, 73%, 61%, 30%, and 9% were resistant to sulfamethoxazole, streptomycin, ampicillin, tetracycline, nalidixic acid, chloramphenicol, and ciprofloxacin, respectively; and of 31 isolates from pork meat 87%, 77%, 39%, 32%, 10% and 10% were resistant to sulfamethoxazole, tetracycline, streptomycin, ampicillin, nalidixic acid, and chloramphenicol, respectively. Three ampicillin-resistant isolates from swine feces carried the same extended-spectrum beta-lactamase gene belonging to bla(CTX-M) group 1. The results of this study confirm the existence of ESBL in S. enterica isolated from food animals. Occurrence of an ESBL producing strain of S. enterica constitutes a public health threat through transmission of these strains to humans via contaminated food or transfer of antimicrobial resistant genes to human pathogens.

• 出版日期2016-11