A highly selective phosphorescent chemodosimeter for cysteine and homocysteine based on platinum(II) complexes

作者：Huang Kewei; Yang Hong; Zhou Zhiguo^*; Chen Huili; Li Fuyou; Yi Tao; Huang Chunhui

来源：Inorganica Chimica Acta, 2009, 362(8): 2577-2580.

DOI：10.1016/j.ica.2008.11.026

• Phosphorescence
• Chemodosimeter
• Platinum complex
• Cysteine
• Homocysteine

A platinum(II) complex Pt(phen)C CC(6)H(4)CHO has been demonstrated as a highly selective phosphorescent chemodosimeter for cysteine and homocysteine. Upon addition of homocysteine or cysteine to its acetonitrile-water solution, an evident luminescent color variation from green to orange was observed. This red-shift of phosphorescence emission could be attributed to formation of a thiazinane through a selective reaction of aldehyde group of Pt(phen)C CC(6)H(4)CHO with cysteine/homocysteine, which was con. rmed by (1)H NMR investigation and density functional theory (DFT) calculations. The further selectivity investigation indicates that it displays high selectivity for homocysteine and cysteine, and therefore can be utilized as cysteine/homocysteine phosphorescent chemodosimeter.

• 出版日期2009-6
• 单位复旦大学