Amplified Photodegradation of Cell-Laden Hydrogels via an Addition-Fragmentation Chain Transfer Reaction

作者:Brown Tobin E; Marozas Ian A; Anseth Kristi S*
来源:Advanced Materials, 2017, 29(11): UNSP 1605001.
DOI:10.1002/adma.201605001

摘要

Hydrogels crosslinked by allyl-sulfide-containing molecules are presented. By exposure to light in the presence of a photoinitiator and a free monofunctional thiol, photodegradation is achieved. Both the gelation and degradation are cytocompatible and allow for cell encapsulation and subsequent release. The photodegradation kinetics and depths attainable are superior to those of traditional cell-laden photodegradable hydrogels.

  • 出版日期2017-3-21