Antioxidant Constituents of Geranium bellum Rose

作者：Camacho Luis Abelardo^*; Gayosso De Lucio Juan A; Torres Valencia J Martin; Munoz Sanchez Jose L; Alarcon Hernandez Ernesto; Lopez Rogelio; Barron Blanca L

来源：Journal of the Mexican Chemical Society, 2008, 52(2): 103-107.

• Geranium bellum Rose
• Geraniaceae
• antioxidant activity
• flavonoids
• tannins
• (1)H and (13)C NMR spectroscopy

Radical scavenging assay-guided fractionation of the antioxidant EtOAc and MeOH extracts from the aerial parts of Geranium bellum resulted in the isolation of beta-sitosterol 3-O-beta-D-glucopiranoside (1), quercetin 3-O-alpha-L-(2 ''-O-acetyl) arabinofuranoside (2), quercetin 3-O-alpha-L-arabinofuranoside (3), quercetin (4), methyl gallate (5), gallic acid (6), methyl brevifolin carboxylate (7), and dehydrochebulic acid trimethyl ester (8). These substances were fully characterized by 1D and 2D NMR spectroscopy as well as by their physical properties. 2,2'-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activities for the extracts, primary fractions and pure compounds were determined. Compounds 2-4 showed very strong ABTS radical scavenging activity, whereas compound 5-8 had moderate activity and compound 1 was weakly active. Compounds 2, 7 and 8 are isolated for the first time from Geranium.

• 出版日期2008-6