Acantholytic squamous cell carcinoma of the gingiva: report of a case and review of the literature

作者：Papadopoulou Erofili^*; Tosios Konstantinos I; Nikitakis Nikolaos; Papadogeorgakis Nikolaos; Sklavounou Andrikopoulou Alexandra

来源：Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, 2010, 109(6): E67-E71.

DOI：10.1016/j.tripleo.2010.01.019

Adenoid squamous cell carcinoma differs from common squamous cell carcinoma in histologic features and its aggressive nature. Microscopically, the tumor shows cystic degeneration of the neoplastic epithelium, producing a prominent alveolar pattern and pseudoglandular structures with acantholytic cells. It occurs most commonly on the lips, rarely intraorally, and it is associated with a poor prognosis. This case concerns a 72-year-old woman who presented with the chief complaint of burning tongue and soreness of the lips. Clinical examination revealed an ulcerated and elevated mass on the edentulous left maxillary ridge, beneath the base of a partial denture. An incisional biopsy rendered the diagnosis of adenoid squamous cell carcinoma. The patient was referred to a specialized maxillofacial surgery center for diagnostic work-up and treatment. She underwent partial maxillectomy and radiotherapy, and 17 months after treatment, she died of uncontrollable recurrence. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;109:e67-e71)

• 出版日期2010-6