Adult Cancer Pain

作者:Swarm Robert*; Abernethy Amy Pickar; Anghelescu Doralina L; Benedetti Costantino; Blinderman Craig D; Boston Barry; Cleeland Charles; Coyle Nessa; deLeon Casasola Oscar A; Eilers June G; Ferrell Betty; Janjan Nora A; Karver Sloan Beth; Levy Michael H; Lynch Maureen; Moryl Natalie; Murphy Barbara A; Ne**it Suzanne A; Oakes Linda; Obbens Eugenie A; Paice Judith A; Rabow Michael W; Syrjala Karen L; Urba Susan; Weinstein Sharon M
来源:Journal of the National Comprehensive Cancer Network, 2010, 8(9): 1046-+.
DOI:10.6004/jnccn.2010.0076

摘要

Pain is one of the most common symptoms associated with cancer. Cancer pain or cancer-related pain is distinct from pain experienced by patients without malignancies. Pain occurs in approximately one quarter of patients with newly diagnosed malignancies, one third of patients undergoing treatment, and three quarters of patients with advanced disease, and is one of the symptoms patients fear most. Unrelieved pain denies patients comfort and greatly affects their activities, motivation, interactions with family and friends, and overall quality of life. The importance of relieving pain and availability of effective therapies make it imperative that physicians and nurses caring for these patients be adept at the assessment and treatment of cancer pain. This requires familiarity with the pathogenesis of cancer pain; pain assessment techniques; common barriers to the delivery of appropriate analgesia; and pertinent pharmacologic, anesthetic, neurosurgical, and behavioral approaches to the treatment of cancer pain. The NCCN Guidelines on adult cancer pain underwent significant revision for 2010. Noteworthy updates include the addition of steps with case examples for converting/rotating one opioid to another, oral morphine to methadone, and any opioid to transdermal fentanyl.