Development of a rapid detection method for eight organophosphate esters in plastic samples from automobile interiors using ultra-performance liquid chromatography tandem mass spectrometry with microwave assisted extraction

作者：Wang, Yiping; Du, Zhenxia^*; Zhang, Yun; Zhou, Lili; Yu, Wenlian

来源：Analytical Methods, 2015, 7(23): 9861-9866.

DOI：10.1039/c5ay02077h

• FLAME RETARDANTS
• WATER SAMPLES
• AIR

A rapid, effective and eco-friendly method for determination of eight organophosphate esters in plastic samples from car interiors by microwave assisted extraction followed by ultra-high performance liquid chromatography combined with tandem mass spectrometry was established. Acetone/ethyl acetate (3/1, v/v) was used as extractant. Response surface methodology was applied as the experimental design strategy to screen and optimize the extraction variables which affected the extraction efficiency, such as the volume of the extraction solvent, the time for extraction, and the temperature of extraction. Baseline separation of eight OPEs was achieved in 4.5 minutes. The method showed excellent linearity 1-250 mu g L-1 for TBEP, TCP, and DPOP; 2-500 mu g L-1 for TPhP; 5-1250 mu g L-1 for TEP; 10-2500 mu g L-1 for TPrP and TCPP; 15-3750 mu g L-1 for TCEP (R > 0.9907). For the eight OPEs, the LODs ranged between 0.25 mu g L-1 and 5 mu g L-1 and the LOQs ranged between 0.5 mu g L-1 and 15 mu g L-1.

• 出版日期2015
• 单位北京化工大学; 中国检验检疫科学研究院