Diurnal variation of the tear osmolarity in normal subjects measured by a new microchip system

作者：Oncel Banu Acikalin^*; Pinarci Eylem; Akova Yonca A

来源：European Journal of Ophthalmology, 2012, 22: S1-S4.

DOI：10.5301/ejo.5000084

• Diurnal variation
• Dry eye
• Osmolarity

PURPOSE. To show the diurnal variation of tear osmolarity in normal subjects. %26lt;br%26gt;METHODS. Thirty volunteers were recruited. Tear osmolarity was measured with TearLab osmolarity system at 3-hour regular intervals between 8:00 AM and 5:00 PM. One-way analysis of variance test was used for statistical analysis. %26lt;br%26gt;RESULTS. Thirty healthy volunteers (all men) with a mean age of 29.6 +/- 4.3 years (range 18-45) were recruited. The difference between measurements at 8:00 AM and 11:00 AM, 8:00 AM and 2:00 PM, 8:00 AM and 5:00 PM, 11:00 AM and 2:00 PM, 11:00 AM and 5:00 PM, and 2:00 PM and 5:00 PM were not statistically significant (one-way analysis of variance test, p%26gt;0.05). %26lt;br%26gt;CONCLUSIONS. In normal subjects, tear osmolarity seems to have a stable profile during the daytime.

• 出版日期2012-6