Assessment of serum KL-6 as a prognostic marker in pulmonary tuberculosis patients

作者：Miwa S^*; Suzuki Y; Shirai M; Ohba H; Kanai M; Eifuku T; Suda T; Hayakawa H; Chida K

来源：International Journal of Tuberculosis and Lung Disease, 2013, 17(2): 240-242.

DOI：10.5588/ijtld.12.0498

• PTB
• KL-6
• serum marker
• prognosis

Although serum Krebs von den Lungen-6 (KL-6) levels are reported to increase in pulmonary tuberculosis (PTB) patients according to disease activity, the relationship between serum KL-6 levels and prognosis remains unclear. In this study, we prospectively examined serum KL-6 levels in 188 PTB patients and assessed 60-day mortality. Univariate and multivariate logistic regression analysis demonstrated that serum KL-6 levels were not significantly associated with prognosis. For receiver operating characteristic analysis, the area under the curve had low accuracy for predicting mortality. These findings indicate that serum KL-6 levels do not perform adequately for use as a prognostic marker in patients with PTB.

• 出版日期2013-2