A feasible method for As speciation in several types of seafood by LC-ICP-MS/MS

作者：Schmidt Lucas; Landero Julio Alberto; Novo Diogo La Rosa; Duarte Fabio Andrei; Mesko Marcia Foster; Caruso Joseph A; Moraes Flores Erico Marlon

来源：Food Chemistry, 2018, 255: 340-347.

DOI：10.1016/j.foodchem.2018.02.079

• Arsenic speciation
• Sample preparation
• Extraction
• Liquid chromatography
• Inductively coupled plasma triple quadrupole mass spectrometry
• Food safety

A method for arsenic speciation in shark, shrimp, squid, oyster and scallop using liquid chromatography coupled to inductively coupled plasma triple quadrupole mass spectrometry (LC-ICP-MS/MS) was proposed. Suitable sensitivity and selectivity by LC-ICP-MS/MS were obtained using 10 mmol L-1 (NH4)(2)HPO4 diluted in 1% methanol (pH 8.65) as mobile phase. Recoveries from 90 to 104% for arsenobetaine (AsB), arsenite [As(III)], dimethylarsinic acid (DMA), monomethylarsonic acid (MMA) and arsenate [As(V)] were obtained for all samples. A certificated reference material was also analyzed and the sum of As species was in agreement with the total As concentration. Limits of quantification (LOQ) for AsB, As(III), DMA, MMA, and As(V) were 6, 30, 6, 12 and 26 ng g(-1), respectively. Higher concentration of AsB was found in all seafood, while As(III) and DMA were found only in oyster. Arsenate was found in squid and scallops, and MMA was below the LOQ in all samples.

• 出版日期2018-7-30