摘要

The study was conducted on the skin samples obtained from glabrous human skin to find out study the density and structure of Meissner's corpuscle (MC) at different sites like finger tips, palm, front of forearm, sole, lips, prepuce of penis, dorsum of hand and dorsum of foot. The skin samples were taken from sixty persons (with age range of 2-72 years); 5 pm thick section were prepared, impregnated with silver and observed under compound light microscope. Density of the MCs was studied by calculating Meissner's Index (MI). Different sites had different MIs, which ranged from 0.28 to 0.96. The highest MI was observed at the finger tip and lowest at the prepuce of penis. The shape and size of the MC has direct relationship with its site and function. Largest size of the MC was at finger tip (120-260 x 64-84 mu m) and the smallest at prepuce of penis (66-84 x 38-52 mu m). In less tactile areas like dorsum of hand and foot, the shape of the MC was globular and its structure simple while as in more sensitive areas like finger tips, the shape changed to oval or cylindrical form with complex structure.