Application of bowel plication combined with early enteral nutrition in the enhanced recovery after surgery for neonates with jejunal atresia

作者：Chen Huan; Geng Qiming; Lu Changgui; Jiang Weiwei; Zhang Jie; Lyu Xiaofeng; Li Wei; Li Hongxing; Tang Weibing

来源：中华胃肠外科杂志, 2017, 20(5).

DOI：10.3760/cma.j.issn.1671-0274.2017.05.012

• Bowel plication
• Early enteral nutrition
• Enhanced recovery after surgery

Objective To evaluate the efficacy of bowel plication combined with early enteral nutrition (EEN) in the enhanced recovery after surgery (ERAS) of jejunal atresia (JA) neonates. Methods Between January 2005 and January 2014, 58 neonates with JA underwent surgical treatment in Children′ s Hospital of Nanjing Medical University. Their clinical data , including operation procedures, ages, birth weight, concomitant diseases, age at surgery, hospital stay, total parenteral nutrition (TPN), postoperative intestinal function recovery (the time to the first oral feeding and the time to oral feeding volume reaching 150 ml ·kg -1·d -1), complications and reoperation, were retrospectively analyzed. Results According to the surgical procedures, the 58 neonates were divided into three groups: control group (18 cases, undergoing atretic segments resection and primary anastomosis), bowel plication group (19 cases, undergoing bowel plication after atretic segments resection and primary anastomosis) and bowel plication combined with EEN group (21 cases, undergoing bowel plication combined with EEN). No significant differences of ages, birth weight, age at operation, and concomitant diseases were found among 3 groups (all P > 0.05). The time of hospital stay, the time to the first oral feeding, the time to oral feeding volume reaching 150 ml·kg-1·d-1, and the time of TPN in bowel plication group were significantly shorter than those of control group [(19.3 ± 4.4) d vs. (22.7 ± 3.1) d, t=2.696, P=0.011;(9.8 ± 3.3 ) d vs. (12.5 ± 3.0) d, t=2.630, P=0.013;(18.5 ± 4.1) d vs. (21.5 ± 2.5) d, t=2.726, P=0.011;(13.1 ± 2.9) d vs. (15.0 ± 2.3) d, t=2.219, P=0.033]. However, above parameters of bowel plication combined with EEN group were significantly shorter than those of bowel plication group [(15.3 ± 3.5) d vs. (19.3 ± 4.4), t = 4.120, P=0.003;(7.7 ± 2.2) d vs. (9.8 ± 3.3) d, t=2.428, P=0.020;(14.8 ± 2.5) d vs. (18.5 ± 4.1) d, t=3.752, P=0.001; (9.5 ± 3.0) vs. (13.1 ± 2.9) d, t=4.370, P=0.000]. Conclusion The bowel plication combined with EEN contributes to the early use of intestinal function , shorten the time to the first oral feeding, and reduces the use of TPN, which can improve the recovery of jejunal atresia neonates.

• 出版日期2017
• 单位南京医科大学