Autophagosome Formation: Tracing the Source

作者:Bernard Amelie; Klionsky Daniel J*
来源:Developmental Cell, 2013, 25(2): 116-117.
DOI:10.1016/j.devcel.2013.04.004

摘要

Although it is well appreciated that autophagy begins with phagophore formation and expansion through lipid acquisition to become the autophagosome, this process remains poorly understood, with the source of autophagosome membrane controversial. Reporting recently in Nature, Hamasaki et al. (2013) suggest that the ER-mitochondria contact sites are involved in phagophore assembly.

  • 出版日期2013-4-29