An oxepinoflavone from Artocarpus elasticus with cytotoxic activity against P-388 cells

作者：Musthapa Iqbal; Juliawaty Lia D; Syah Yana M^*; Hakim Euis H; Latip Jalifah; Ghisalberti Emilio L

来源：Archives of Pharmacal Research, 2009, 32(2): 191-194.

DOI：10.1007/s12272-009-1134-0

• Artocarpus elasticus
• Flavonoids
• Oxepinoflavone
• Artoindonesianin E1
• Cytotoxicity
• P-388 cells

A new oxepinoflavone, artoindonesianin E1 (1), was isolated from the wood of Artocarpus elasticus, along with four known prenylated flavones: artocarpin (2), cycloartocarpin (3), cudraflavones A (4) and C (5). The structure of the new compound was identified by spectroscopic methods. Upon cytotoxic evaluation against murine leukemia P-388 cells, the new compound showed IC(50) 5.0 mu g/mL.

• 出版日期2009-2