A Multi-Parameter Decoupling Method with a Lamb Wave Sensor for Improving the Selectivity of Label-Free Liquid Detection

作者：Zhou, Lianqun; Wu, Yihui^*; Xuan, Ming; Manceau, Jean-Francois; Bastien, Francois

来源：Sensors (Switzerland), 2012, 12(8): 10369-10380.

DOI：10.3390/s120810369

• Lamb wave sensor
• density
• sound velocity
• viscosity
• determination of multi-parameters

In this paper, a liquid multi-parameter decoupling method with only one Lamb wave sensor is presented. In a Lamb wave sensor, antisymmetric modes (A(01) mode for low frequency, A(03) mode for high frequency) and symmetric modes (S-0 mode) are used to detect multiple parameters of a liquid, such as its density, sound velocity, and viscosity. We found they can play very different roles in the detections. For example, the A(01) mode is very sensitive to the liquid's density but the A(03) mode is sensitive to the sound velocity. Here, the A(0) mode is used to identify the density of the detected liquid and with this density value we obtained the viscosity by the amplitude shifts of the S0 mode. This could be a way to distinguish an unknown liquid with high sensitivity or to solve the problem of selectivity of label-free detection on biosensors.

• 出版日期2012-8
• 单位中国科学院长春光学精密机械与物理研究所; 应用光学国家重点实验室; 中国科学院苏州生物医学工程技术研究所