A new one-pot hydroformylation/Strecker synthesis as a versatile synthetic tool for polyfunctional compounds and functionalization of dendrimers

作者:Subhani Muhammad Afzal; Mueller Kai Sven; Koc Fikret; Eilbracht Peter*
来源:Organic and Biomolecular Chemistry, 2009, 7(19): 4000-4008.
DOI:10.1039/b907787a

摘要

A versatile and high yielding one-pot hydroformylation/Strecker synthesis is reported for the synthesis of various alpha-aminonitriles. This methodology allows functionalization of dendrimers (e.g. polyamines 4-7) and hyper branched polymers (e.g. polyallyl glycerol 12) to give corresponding dendritic structures with alpha-aminonitriles and/or amino acids in the outer shell in good to excellent yields.

  • 出版日期2009