NKTeeing Up B Cell Responses to Viral Infection

作者：Fontana Mary F; Pepper Marion^*

来源：Immunity, 2018, 48(2): 198-200.

DOI：10.1016/j.immuni.2018.02.008

Activated B cells mature in germinal centers (GCs), but GC initiation during infection is poorly understood. Gaya et al. (2018) show that NKT cells, activated by CD169(+) macrophages, produce an early wave of interleukin-4 (IL-4) that promotes GC formation during viral infection.

• 出版日期2018-2-20