A Comparison between Brachial and Echocardiographic Systolic Time Intervals

作者：Su Ho Ming; Lin Tsung Hsien; Hsu Po Chao; Chu Chun Yuan; Lee Wen Hsien; Chen Szu Chia^*; Lee Chee Siong; Voon Wen Chol; Lai Wen Ter; Sheu Sheng Hsiung

来源：PLos One, 2013, 8(2): e55840.

DOI：10.1371/journal.pone.0055840

Systolic time interval (STI) is an established noninvasive technique for the assessment of cardiac function. Brachial STIs can be automatically determined by an ankle-brachial index (ABI)-form device. The aims of this study are to evaluate whether the STIs measured from ABI-form device can represent those measured from echocardiography and to compare the diagnostic values of brachial and echocardiographic STIs in the prediction of left ventricular ejection fraction (LVEF) %26lt;50%. A total of 849 patients were included in the study. Brachial pre-ejection period (bPEP) and brachial ejection time (bET) were measured using an ABI-form device and pre-ejection period (PEP) and ejection time (ET) were measured from echocardiography. Agreement was assessed by correlation coefficient and Bland-Altman plot. Brachial STIs had a significant correlation with echocardiographic STIs (r = 0.644, P%26lt;0.001 for bPEP and PEP; r = 0.850, P%26lt;0.001 for bET and ET; r = 0.708, P%26lt;0.001 for bPEP/bET and PEP/ET). The disagreement between brachial and echocardiographic STIs (brachial STIs minus echocardiographic STIs) was 28.55 ms for bPEP and PEP, -4.15 ms for bET and ET and -0.11 for bPEP/bET and PEP/ET. The areas under the curve for bPEP/bET and PEP/ET in the prediction of LVEF %26lt;50% were 0.771 and 0.765, respectively. Brachial STIs were good alternatives to STIs obtained from echocardiography and also helpful in prediction of LVEF %26lt;50%. Brachial STIs automatically obtained from an ABI-form device may be helpful for evaluation of left ventricular systolic dysfunction.

• 出版日期2013-2-7