An Efficient Copper-mediated 1,3-Dipolar Cycloaddition of Pyrazolidinone-based Dipoles to Terminal Alkynes to Produce N,N-Bicyclic Pyrazolidinone Derivatives

作者：Oishi Takamichi; Yoshimura Kazuaki; Yamaguchi Kazuya; Mizuno Noritaka^*

来源：Chemistry Letters, 2010, 39(10): 1086-1087.

DOI：10.1246/cl.2010.1086

A simple dinuclear copper complex [Cu(mu-OH)(tmen)](2)Cl-2 (tmen = N,N,N',N'-tetramethylethylenediamine) could act as an effective precatalyst for the 1,3-dipolar cycloaddition of pyrazolidinone-based dipoles to terminal alkynes to produce the corresponding N,N-bicyclic pyrazolidinone derivatives

• 出版日期2010-10-5