Marine Toxins with Spiroimine Rings: Total Synthesis of Pinnatoxin A

作者：Beaumont Stephane; Ilardi Elizabeth A; Tappin Nicholas D C; Zakarian Armen^*

来源：European Journal of Organic Chemistry, 2010, (30): 5743-5765.

DOI：10.1002/e.joc.201000842

• Natural products
• Total synthesis
• Marine toxins
• Spiroimine natural products
• Pinnatoxin
• Spiro compounds

This microreview provides a compilation of synthetic approaches and total syntheses of pinnatoxin A in a survey of the literature up to early 2010. Pinnatoxin A is the first discovered and representative member of a fascinating group of potent marine toxins that share a spiroimine subunit as a unifying structural element.

• 出版日期2010-10