Natural products from microbes associated with insects

作者:Beemelmanns Christine*; Guo Huijuan; Rischer Maja; Poulsen Michael
来源:Beilstein Journal of Organic Chemistry, 2016, 12: 314-327.
DOI:10.3762/bjoc.12.34

摘要

Here we review discoveries of secondary metabolites from microbes associated with insects. We mainly focus on natural products, where the ecological role has been at least partially elucidated, and/or the pharmaceutical properties evaluated, and on compounds with unique structural features. We demonstrate that the exploration of specific microbial-host interactions, in combination with multidisciplinary dereplication processes, has emerged as a successful strategy to identify novel chemical entities and to shed light on the ecology and evolution of defensive associations.

  • 出版日期2016-2-19