A mechanism of raft formation on both plasma membrane layers

作者:Sornbundit Kan*; Modchang Charin; Triampo Wannapong; Triampo Darapond; Nuttavut Narin
来源:The European Physical Journal - Applied Physics, 2013, 64(1): 11101.
DOI:10.1051/epjap/2013130210

摘要

A double-layered membrane model is proposed to explain raft formation and induction on extracellular (outer) and cytoplasmic (inner) leaflets of plasma membranes in a situation where only the outer layer has a tendency to phase-separate. In the model, lipid exchange with the surrounding medium is allowed on both layers, but lipid exchange between layers is not allowed. Simulations display domain stabilization on both layers. The effect of the lipid recycling frequencies on stationary domain sizes is also investigated. It is found that stationary domain sizes decrease when lipid recycling frequencies are stronger. Linear stability analysis is used to verify the results.

  • 出版日期2013-10

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