Promoting prudent use of antibiotics: the experience from a multifaceted regional campaign in Greece

作者：Plachouras Diamantis^*; Antoniadou Anastasia; Giannitsioti Efthymia; Galani Lambrini; Katsarolis Ioannis; Kavatha Dimitra; Koukos George; Panagopoulos Periklis; Papadopoulos Antonios; Poulakou Garyphalia; Sakka Vissaria; Souli Maria; Sybardi Styliani; Tsiodras Sotirios; Kanellakopoulou Kyriaki; Giamarellou Helen

来源：BMC Public Health, 2014, 14(1): 866.

DOI：10.1186/1471-2458-14-866

• Antimicrobial consumption
• Academic detailing
• Public education

Background: Antibiotic resistance, a major public health problem, has been linked to antibiotic consumption. In Greece both consumption and resistance rates are among the highest in Europe. A multifaceted campaign targeting both physicians and parents of school children was implemented for the first time in order to educate the public and update doctors, aiming to promote judicious use of antibiotics and hopefully decrease its consumption.
Methods: The programme consisted of a public education campaign and academic detailing of primary care physicians in the district of Corinth in Peloponnese. The experience and perceptions of parents were recorded in the meetings in the form of course evaluation and assessment, anonymous questionnaires. The use of Rapid Antigen Detection Test (RADT) for streptococcal pharyngitis by primary care physicians was also assessed by use of anonymous questionnaires. Antibiotic consumption was compared before and after the programme between the district of Corinth and the other districts of Peloponnese, as well as at a national level.
Results: Antibiotic consumption remained unaltered at 26 Defined daily doses per 1000 Inhabitants per Day (DID) in accordance with the trend in other regions and at a national level. However, the utilization of Amoxycillin and Penicillin was increased by 34.3%, while the use of other antimicrobial classes including macrolides, cephalosporins and fluoroquinolones decreased by 6.4-21.9%. The use of RADT did not lead to a significantly decreased antimicrobial consumption.
Conclusions: A multifaceted educational programme targeting both the general public and primary care physicians was associated with rationalization in the choice of antimicrobial. A reduction in the total antimicrobial consumption was not achieved.

• 出版日期2014-8-22