科研之友
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摘要
The efficient asymmetric Michael addition/intramolecular cyclization of malononitrile with dienones catalyzed by a chiral bifunctional tertiary amine-squaramide catalyst for the synthesis of chiral 2-amino-4H-chromene-3-carbonitrile derivatives was developed. The corresponding products were obtained in good to excellent yields (up to 99%) with excellent enantioselectivities (up to 98%ee) for most of the bisarylidenecyclopentanones.
- 出版日期2014-10
- 单位北京理工大学
