Antioxidant and anti-inflammatory activity of Moussonia deppeana

作者：Dominguez Ortiz Miguel A^*; Munoz Muniz Omar; Virginia Garcia Rodriguez Rosa; Vazquez Hernandez Maribel; Gallegos Estudillo Janeth; Samuel Cruz Sanchez Jesus

来源：Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas, 2010, 9(1): 13-19.

• Anti-inflammatory
• Antioxidant
• Moussiana deppeana
• Ethnopharmacology
• Medicinal Plants

Moussonia deppeana (Schldl. & Cham) Hanst is a species of Mexican Medicinal Flora used in Veracruz state, to treat sufferings related to stomach pain, renal diseases, cough, tumors and inflammation. Obtained results showed that EtOAc extract was the most active in free radical scavenging test DPPH (CI(50) 18.3 +/- 3.4 mu g/mL) with 41% of reducing power respect to ascorbic acid and total content of polyphenols was smaller (328.9 +/- 7.6 mg GAE/g) than the found in the ethanol extract (388.6 +/- 6.2 mg GAE/g). Anti-inflammatory activity was evaluated by topical application of the extracts (doses 2 mg/ear) giving a greater inhibition in hexane and EtOAc extracts (39 and 28%, respectively). The model of paw edema was evaluated in EtOAc extract, observing a similar inhibition to indomethacin (43% with 100 mg of dose) at the first hour. These results support the biological effect attributed in their traditional use.

• 出版日期2010-1