科研之友
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摘要
This review highlights recent progress made in the understanding of the underlying neurobiology of depressive disorders based on positron emission tomography (PET) and single photon emission computed tomography (SPECT). These radioisotope techniques allow in vivo molecular imaging, in particular of the brain monoaminergic system, and contribute to the identification of affected neuronal circuits underlying mood disturbances. Their routine clinical usage, however, has not been established yet, but especially PET holds promise to be part of an integrative clinical approach contributing to individualized treatment of patients with depression.
- 出版日期2009
