Antioxidant activity and antitumor activity (in vitro) of xyloglucan selenious ester and surfated xyloglucan

作者：Cao Yu^*; Ikeda Isao

来源：International Journal of Biological Macromolecules, 2009, 45(3): 231-235.

DOI：10.1016/j.ijbiomac.2009.05.007

• Xyloglucan selenious ester
• Sulfated xyloglucan
• Antioxidant
• Antitumor
• Selenition

Two kinds of xyloglucan derivatives (xyloglucan selenious ester and sulfated xyloglucan) were prepared and evaluated on antioxidant activity and antitumor activity. Compared with xyloglucan, xyloglucan derivatives have new bioactivity against oxidative damage and tumor. Furthermore, xyloglucan selenious ester is more potent than sulfated xyloglucan at antioxidant activity and antitumor activity in vitro. The current data suggest for the first time that selenition of xyloglucan significantly increases its bioactivity and the chemical modification of polysaccharide may allow the preparation of derivatives with new properties and a variety of applications.

• 出版日期2009-10-1
• 单位华中师范大学