Ameliorating Effects of a Nopal (Opuntia ficus-indica) Complex on Blood Glucose in db/db Mice

作者：Yoon Jin A; Lee Sung Joon; Kim Han Kyeom; Son Yong Suk^*

来源：Food Science and Biotechnology, 2011, 20(1): 255-259.

DOI：10.1007/s10068-011-0035-4

• Opuntia ficus-indica
• hypoglycemic
• insulin
• pancreatic islet
• db/db mice

This study investigated the effects of a nopal (Opuntia ficus-indica) complex (OF) on blood glucose metabolism in db/db mice for 4 weeks. Food and water intake significantly decreased in OF-treated mice compared to controls (p < 0.05). In addition, blood glucose and plasma insulin levels were significantly reduced in the OF-treated group compared to the controls (p < 0.05). Histopathological analysis showed that the morphology of pancreatic islets was improved in the OF-treated db/db mice. Immunohistochemistry of the pancreatic islets showed that insulin production and the number of beta-cells apparently increased.

• 出版日期2011-2