Voltammetric sensor for trichloroacetic acid using a glassy carbon electrode modified with Au@Ag nanorods and hemoglobin

作者：Qian, Dongping; Li, Weibo; Chen, Fangting; Huang, Ying; Bao, Ning; Gu, Haiying^*; Yu, Chunmei^*

来源：Microchimica Acta, 2017, 184(7): 1977-1985.

DOI：10.1007/s00604-017-2175-6

• Core-shell nanorods
• Self-assembly
• Electrocatalysis
• Amperometry
• Biosensor
• Laviron equation

Core-shell Au@Ag nanorods (Ag@GNRs) were synthesized and utilized to construct a voltammetric biosensor for trichloroacetic acid (TCA). The biosensor was prepared by immobilizing hemoglobin (Hb) on a glassy carbon electrode (GCE) that was modified with the Ag@GNRs. Cyclic voltammetry revealed a pair of symmetric redox peaks, indicating that direct electron transfer occurs at the Hb on the Ag@GNR-film. The electron transfer rate constant is as high as 2.32 s(-1). The good electrocatalytic capability and large surface area of the Ag@GNR-film is beneficial in terms of electron transfer between Hb and the underlying electrode. The modified GCE, best operated at -0.4 V (vs. SCE), exhibits electrocatalytic activity toward TCA in the 0.16 mu M to 1.7 mu M concentration range, with a 0.12 mu M detection limit (at an S/N ratio of 3).

• 出版日期2017-7
• 单位南通大学