A cocrystal of 3 alpha-hydroxytirucalla-8,24-dien-21-oic acid and 3 beta-fluorotirucalla-7,24-dien-21-oic acid (0.897:0.103)

作者：Yousuf S; Kamdem R S T; Wafo P; Ngadjui B T; Fun Hoong Kun^*

来源：Acta Crystallographica Section E-Structure Reports Online, 2011, 67: O1015-U1735.

DOI：10.1107/S1600536811011159

The title compound, 0.897C(30)H(48)O(3).0.103C(30)H(47)O(2)F is a co-crystal of two triterpenes isolated from the resin of Canarium schweinfurthiiand Engl. Both triterpenes consists of four trans-fused rings having chair/half-chair/half-chair and envelope conformations. The molecular conformations are stabilized by intramolecular C-H...O hydrogen bonds, forming rings of S(7) graph-set motif. In the crystal, molecules are linked by intermolecular O-H...O and C-H...O interactions, forming sheets parallel to (001). All atoms. excepting the axially-oriented hydroxyl group in the major component and the equatorially-oriented fluorine atom in the minor component, are overlapping.

• 出版日期2011-4