Assessment and Modulation of Neural Plasticity in Rehabilitation With Transcranial Magnetic Stimulation

作者：Bashir Shahid; Mizrahi Ilan; Weaver Kayleen; Fregni Felipe^*; Pascual Leone Alvaro

来源：PM&R, 2010, 2(12): S253-S268.

DOI：10.1016/j.pmrj.2010.10.015

Despite intensive efforts to improve outcomes after acquired brain injury, functional recovery is often limited. One reason for this limitation is the challenge in assessing and guiding plasticity after brain injury. In this context, transcranial magnetic stimulation (TMS), a noninvasive tool of brain stimulation, could play a major role. TMS has been shown to be a reliable tool for measuring plastic changes in the motor cortex associated with interventions in the motor system, such as motor training and motor cortex stimulation. In addition, as illustrated by the experience in promoting recovery from stroke, TMS is a promising therapeutic tool to minimize motor, speech, cognitive, and mood deficits. In this review, we will focus on stroke to discuss how TMS can provide insights into the mechanisms of neurologic recovery and how it can be used for measurement and modulation of plasticity after an acquired brain insult. PM R 2010;2:S253-S268

• 出版日期2010-12