USE OF 3.0-T MRI FOR STEREOTACTIC RADIOSURGERY PLANNING FOR TREATMENT OF BRAIN METASTASES: A SINGLE-INSTITUTION RETROSPECTIVE REVIEW

作者：Saconn Paul A; Shaw Edward G; Chan Michael D; Squire Sarah E; Johnson Annette J; McMullen Kevin P; Tatter Stephen B; Ellis Thomas L; Lovato James; Bourland J Daniel; Ekstrand Kenneth E; DeGuzman Allan F; Munley Michael T^*

来源：International Journal of Radiation Oncology, Biology, Physics, 2010, 78(4): 1142-1146.

DOI：10.1016/j.ijrobp.2010.05.049

• Radiosurgery
• Brain metastases
• MRI

Purpose: To investigate the efficacy of 3.0-T magnetic resonance imaging (MRI) for detecting brain metastases for stereotactic radiosurgery (SRS) planning.
Methods and Materials: All adult patients scheduled for SRS treatment for brain metastases at our institution between October 2005 and January 2008 were eligible for analysis. All patients underwent radiosurgery treatment planning 3.0-T MRI on the day of scheduled radiosurgery and a diagnostic 1.5-T MRI in the days or weeks prior to radiosurgery for comparison. Both scans were interpreted by neuroradiologists who reported their findings in the radiology reports. We performed a retrospective review of the radiology reports to determine the number of brain metastases identified using each MRI system.
Results: Of 254 patients scheduled for treatment from October 2005 to January 2008, 138 patients had radiology reports that explicitly described the number of metastases identified on both scans. With a median interval of 17 days (range, 1-82) between scans, the number of metastases detected using 1.5-T MRI system ranged from 1 to 5 and from 1 to 8 using the 3.0 T-MRI system. Twenty-two percent of patients were found to have a greater number of metastases with the 3.0 T-MRI system. The difference in number of metastases detected between the two scans for the entire cohort ranged from 0 to 6. Neither histology (p = 0.52 by chi-sq test) nor time between scans (p = 0.62 by linear regression) were significantly associated with the difference in number of metastases between scans.
Conclusions: The 3.0-T MRI system appears to be superior to a 1.5-T MRI system for detecting brain metastases, which may have significant implications in determining the appropriate treatment modality. Our findings suggest the need for a prospectively designed study to further evaluate the use of a 3.0 T-MRI system for stereotactic radiosurgery planning in the treatment of brain metastases.

• 出版日期2010-11-15