Depressed Brainstem Auditory Function in Children With Cerebral Palsy

作者：Jiang Ze D^*; Wu Yun Y; Liu Xian Y; Wilkinson Andrew R

来源：Journal of Child Neurology, 2011, 26(3): 272-278.

DOI：10.1177/0883073810379913

• auditory dysfunction
• brainstem auditory evoked response
• neurodevelopmental disability
• hearing

Brainstem auditory evoked responses were studied to examine brainstem auditory function in 80 children with cerebral palsy. The response waveform, particularly later waves, tended to be depressed. Thirty-three ( 41.3%) showed abnormal results. The main abnormality was reduced wave V amplitude. Other abnormalities were decreased V/I amplitude ratio, missing waves, prolonged I-V interval, and increased interaural difference in I-V interval. The abnormalities were persistent during the follow-up. In contrast to common findings in the responses in progressive neurologies, abnormalities in interpeak intervals were rare in children with cerebral palsy. There were some characteristic changes in the responses in certain etiologies. These results suggest that brainstem auditory function in children with cerebral palsy is depressed, which may be owing to decreased or altered neural firing or synchrony in the auditory brainstem. A detailed analysis of central components of the responses is valuable in detecting central auditory dysfunction in children with cerebral palsy.

• 出版日期2011-3
• 单位复旦大学