Assessment of Biochemical Characteristics of the Saliva Using Fourier Transform Mid-Infrared Spectroscopy

作者：Khaustova S A^*; Shkurnikov M U; Grebenyuk E S; Artyushenko V G; Tonevitsky A G

来源：Bulletin of Experimental Biology and Medicine, 2009, 148(5): 841-844.

DOI：10.1007/s10517-010-0831-5

• saliva
• infrared spectroscopy
• attenuated total reflection infrared spectroscopy
• non-invasive diagnostics

We developed a method of rapid assay for biochemical properties of the saliva based on attenuated total reflection infrared spectroscopy. This method allows evaluating saliva composition within 5 min without sample preparation; 10 mu l sample is enough for the analysis. The concentration of total protein, glucose, secretory immunoglobulin A, urea, amylase, cortisol, inorganic phosphate in the saliva can also be measured. Precision and reproducibility of the evaluated parameters are comparable to those obtained by routine clinical analysis.

• 出版日期2009-11