An unusual presentation of infective endocarditis: Transient encephalopathy with reversible lesions in corpus callosum and white matter

作者：Yang, Shi-Lin; Zhu, Ming; Wang, Feng; Liu, Wen-Jing; Wang, Yan; Wu, Yun-Cheng^*

来源：Neurology Asia, 2017, 22(4): 373-376.

• Encephalopathy
• reversible lesion
• corpus callosum
• MERS
• infective endocarditis
• Staphylococcus aureus

Clinical mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a clinic-radiological syndrome, which has been reported to be associated with many conditions and the most common pathogens are virus. However, bacteria are rare pathogens for MERS. We report a 20-year-old man diagnosed with definite infective endocarditis, who presented with transient encephalopathy with reversible lesions in the entire corpus callosum and bilateral white matter on magnetic resonance imaging (MRI). The blood culture indicated a Staphylococcus aureus infection. His neurological manifestation improved and imaging abnormalities faded after receiving a combination of intravenous immunoglobulin, methylprednisolone, and antibiotics. Clinicians should be aware of transient encephalopathy with reversible callosal lesions as a potential unusual presentation of infective endocarditis.

• 出版日期2017-12
• 单位上海交通大学; 上海市精神卫生中心