Adaptation to Starvation: Translating a Matter of Life or Death

作者：Manning Brendan D^*

来源：Cancer Cell, 2013, 23(6): 713-715.

DOI：10.1016/j.ccr.2013.05.012

There is much interest in defining the nutrient dependencies of cancer cells and their mechanisms of adaptation to nutrient depletion. In a recent issue of Cell, Leprivier and colleagues demonstrate that eEF2K, which can inhibit translation elongation acutely during protein synthesis, is a critical switch in the survival versus death fate of starved cancer cells.

• 出版日期2013-6-10