A phylogenetic study of canine parvovirus type 2c in midwestern Brazil

作者：Fontana Danubia S; Rocha Paulo Ricardo D; Cruz Raquel A S; Lopes Leticya L; Melo Andreia L T; Silveira Marcelo M; Aguiar Daniel M; Pescador Caroline A^*

来源：Pesquisa Veterinaria Brasileira, 2013, 33(2): 214-218.

DOI：10.1590/S0100-736X2013000200013

• Canine parvovirus
• enteritis
• PCR
• DNA
• sequencing

Since the late 1970s, canine parvovirus type 2 (CPV-2) has emerged as a causative agent of fatal severe acute hemorrhagic enteritis in dogs. To date, three antigenic types of CPV-2 were described worldwide (CPV-2a/b/c). This study was conducted to determine the variants of CPV-2 circulating in dogs from the Cuiaba Municipality in Midwestern Brazil. Out of 50 fecal samples, collected between 2009 and 2011, 27 tested positive for CPV-2. A 583 bp fragment of the VP2 gene was amplified by PCR, 13 representative samples were analyzed further by DNA sequencing. All strains were characterized as CPV-2c, displayed a low genetic variability although observed several amino acid substitution. These findings indicated that CPV-2c has been circulating in dogs from the Cuiaba Municipality in Midwestern Brazil.

• 出版日期2013-2