An efficient, recoverable fluorous organocatalyst for accelerating the DABCO-promoted Morita-Baylis-Hillman reaction

作者：Huang Yi Bo; Yi Wen Bin; Cai Chun^*

来源：Chinese Chemical Letters, 2011, 22(9): 1055-1058.

DOI：10.1016/j.cclet.2011.03.010

• Organocatalyst
• Morita-Baylis-Hillman reaction
• Fluorous solid phase extraction (F-SPE)

A convenient method for Morita-Baylis-Hillman reaction of arylaldehydes with methyl acrylate has been developed by using fluorous-tag organocatalyst 1[4-(perfluorooctyl)phenyl]-3-phenylthiourea and DABCO at room temperature. The fluorous organocatalyst could be recovered from the reaction mixture by fluorous solid-phase extraction (F-SPE) with excellent purity for direct reuse.

• 出版日期2011-9
• 单位南京大学