Double-valve Replacement for Mitral and Aortic Regurgitation in a Patient with Libman-Sacks Endocarditis

作者：Hachiya Kenta; Wakami Kazuaki; Tani Tomomitsu; Yoshida Atsuhiro; Suzuki Shugo; Suda Hisao; Ohte Nobuyuki^*

来源：Internal Medicine, 2014, 53(16): 1769-1773.

DOI：10.2169/internalmedicine.53.2232

• antiphospholipid syndrome
• double-valve replacement
• Libman-Sacks endocarditis
• regurgitation
• systemic lupus erythematosus

A 53-year-old woman with systemic lupus erythematosus and antiphospholipid syndrome presented with central nervous system (CNS) lupus and vegetation of the mitral and aortic valves. Her CNS lupus was relieved with methylprednisolone pulse therapy; however, her mitral regurgitation worsened, and she developed acute decompensated heart failure. The mitral and aortic valves were replaced with mechanical heart valves. Microscopic examination of the excised valves showed no bacterial invasion, and Libman-Sacks (LS) endocarditis of both valves was confirmed. This was a case of LS endocarditis with clear vegetation that spread over the mitral and aortic valves.

• 出版日期2014