Higher Fasting Plasma Glucose Levels, within the Normal Range, are Associated with Decreased Processing Speed in High Functioning Young Elderly

作者：Raizes Meytal^*; Elkana Odelia; Franko Motty; Springer Ramit Ravona; Segev Shlomo; Beeri Michal Schnaider

来源：Journal of Alzheimer's Disease, 2016, 49(3): 589-592.

DOI：10.3233/JAD-150433

• Plasma glucose level
• cognitive function
• processing speed
• type 2 diabetes

We explored the association of plasma glucose levels within the normal range with processing speed in high functioning young elderly, free of type 2 diabetes mellitus (T2DM). A sample of 41 participants (mean age = 64.7, SD = 10; glucose 94.5 mg/dL, SD = 9.3), were examined with a computerized cognitive battery. Hierarchical linear regression analysis showed that higher plasma glucose levels, albeit within the normal range (<110 mg/dL), were associated with longer reaction times (p < 0.01). These findings suggest that even in the subclinical range and in the absence of T2DM, monitoring plasma glucose levels may have an impact on cognitive function.

• 出版日期2016
• 单位河北医科大学