Umbilical Cord as Prospective Source for Mesenchymal Stem Cell-Based Therapy

作者:Arutyunyan Irina; Elchaninov Andrey; Makarov Andrey; Fatkhudinov Timur
来源:Stem Cells International, 2016, 2016: 6901286.
DOI:10.1155/2016/6901286

摘要

The paper presents current evidence on the properties of human umbilical cord-derived mesenchymal stem cells, including origin, proliferative potential, plasticity, stability of karyotype and phenotype, transcriptome, secretome, and immunomodulatory activity. A review of preclinical studies and clinical trials using this cell type is performed. Prospects for the use of mesenchymal stem cells, derived from the umbilical cord, in cell transplantation are associated with the need for specialized biobanking and transplant standardization criteria.

  • 出版日期2016