Novel process windows Part 2-Coming research in ERC advanced grant

作者：Hessel Volker^*; Wang Qi

来源：Chimica Oggi-Chemistry Today, 2011, 29(5): 70-+.

Novel Process Windows (NPW) is the use of highly intensified, unusual and typically harsh process conditions to boost micro process technology and flow chemistry for the production of high-added value fine chemicals, pharmaceuticals, etc. It is far from conventional processing and also from 'normal' micro processing, and enables "flash chemistry" (1) via kinetic-chemistry means tailored to the capability of the microreactors, whereas the micro processing on its own addresses mainly mass and heat transfer and safety issues. In this review, there are two parts introduced. In Part 1, we would like to give a short review on this subject and outline the coming research funded by the ERC Advanced Grant "Novel Process Windows" of Prof. Dr. Volker Hessel at Eindhoven University of Technology (TU/e) in the Netherlands. In Part 2, the details of the coming research in ERC Advanced Grant will be introduced. This truly comprehensive and holistic research comprises four projects with different facets of Novel Process Windows; starting from a molecular-mechanistic (New Chemical Transformations) and kinetic scale (High-Temperature / Pressure Processing) via the scale of reaction environment (Solvent-free Operation and Tuneable / Reactive Solvents) up to a process scale (Process Integration and Simplification). These individual measures are bundled and directed by a horizontal, generic project for deriving cross-cutting insight amongst the four NPW themes and to evaluate these through cost and life-cycle analysis. This paper is about Part 2.

• 出版日期2011-10