Allergen mimotopes

作者:Riemer A; Scheiner O; Jensen Jarolim E*
来源:Methods, 2004, 32(3): 321-327.
DOI:10.1016/j.ymeth.2003.08.010

摘要

The causative treatment of type I allergies is a long pursued goal in immunology. To design safe and efficient vaccine preparations, the interaction of the allergen and the symptom-inducing IgE antibodies still needs to be better understood. In this article, we describe the use of the phage display technique in allergy. It yields epitope mimics, so-called mimotopes, which can be employed for both, investigation of allergen-IgE interactions and definition of safe novel vaccines.

  • 出版日期2004-3

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