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摘要
The synthesis of 3-aryl-5-pentyl-1,2,4-oxadiazoles from carboxylic acid esters and arylamidoximes in the presence of potassium carbonate is described. The reaction was carried out in a microwave oven without any solvent in much shorter time and in good yields. The structures of the synthesized compounds were elucidated using IR, H-1 and C-13 NMR spectroscopy and elemental analysis and their antiproliferative activities was evaluated against three different human cell lines.
- 出版日期2014-3
