Ultrasensitive, Rapid, and Selective Detection of Mercury Using Graphene Assisted Laser Desorption/Ionization Mass Spectrometry

作者：Abdelhamid, Hani Nasser; Wu, Hui Fen^*

来源：Journal of the American Society for Mass Spectrometry, 2014, 25(5): 861-868.

DOI：10.1007/s13361-014-0825-z

• Graphene
• Mass spectrometry
• Mercury
• Biosensing
• Selective

We report an extremely sensitive and specific detection of mercuric ions (Hg2 ) based on graphene assisted laser desorption/ionization mass spectrometry (GALDI-MS). Combining the highly selective coordination interactions between thymine (T) and Hg2 , we present a simple, effective, and novel approach, based on pi-pi interactions of the T-Hg2 -T complex and G that can serve as a platform and matrix for GALDI-MS. The present sensor not only exhibits high selectivity and sensitivity (picomolar) to Hg2 in aqueous solution, but also can elucidate the chemical structures of the metal complexes. The significant advantage in the current approach is that there is no need for a sophisticated instrument, and no sample pretreatment is required to detect the Hg2 ions.

• 出版日期2014-5
• 单位中山大学; 河北医科大学