New Dual Functional Salts Based on Cationic Derivative of Plant Resistance Inducer-Benzo[1.2.3]thiadiazole-7-carbothioic Acid, S-Methyl Ester

作者：Smiglak Marcin^*; Kukawka Rafal; Lewandowski Piotr; Budziszewska Marta; Obrepalska Steplowska Aleksandra; Krawczyk Krzysztof; Zwolinska Agnieszka; Pospieszny Henryk

来源：ACS Sustainable Chemistry and Engineering, 2016, 4(6): 3344-3351.

DOI：10.1021/acssuschemeng.6b00398

• Crop protection agents
• Sustainable chemistry
• Antiviral agents
• Systemic acquired resistance
• Quaternary ammonium salts
• Chemical inducers of plant resistance

Plant resistance induction is one of the most promising ways to support plants in fights against pathogens, especially viruses, due to the fact there are no plant protection agents acting directly on them. Certain chemicals, including benzo[1.2.3]thiadiazole-7-carbothioic acid, S-methyl ester (BTH) and its derivatives, were discovered as effective inducers of plant immunity. In this article, new BTH derivatives, in the form of organic salts composed of cations based on the plant resistance inducer BTH and anions introduced in order to modify physical (solubility in water, dissolution rate, thermal stability, melting points, pK(a) and logP values), and biological (antibacterial) properties are presented. The physical properties of resulting salts were altered by, for example, changing water solubility and also through the introduction of a second ion with a biological bacteriostatic and bactericidal properties against Gram-positive and Gram-negative bacteria). The major impact this new approach in plant protection may have is that the synthetic plant resistance inducers (used in very low dosages) may in the future become an alternative to the pesticides commonly used in large amounts, thus significantly reducing the use of harmful chemicals in agriculture and their negative impact on the environment and human health.

• 出版日期2016-6