科研之友
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摘要
Purpose: To compare the clinical outcomes of two-port laparoscopic donor nephrectomy (TPLDN) vs hand-assisted laparoscopic donor nephrectomy (HALDN). %26lt;br%26gt;Patients and Methods: Between November 2010 and March 2012, 100 kidney donors scheduled for left nephrectomy were alternatively assigned to HALDN or TPLDN in a 1: 1 fashion. All procedures were performed by the same laparoscopic surgeon. Demographic data and intraoperative and early postoperative data were collected prospectively and analyzed. %26lt;br%26gt;Results: There was no difference in the operating time (133 +/- 12 vs 142 +/- 17 min, P = 0.07), blood loss (55 +/- 46 vs 58 +/- 52 mL, P = 0.84), complication rate (10% vs 12%, P = 0.74), and length of hospital stay (3.8 +/- 0.8 vs 4.1 +/- 2.8 days, P = 0.5) between the HALDN and TPLDN groups. The warm ischemia time was longer in the TPLDN group (2.2 +/- 0.7 vs 3.5 +/- 0.9 min, P %26lt; 0.001). No statistically significant differences were found in the analgesic requirement and the visual analog pain scores. There was a trend toward quicker return to 100% recovery in the TPLDN group (60 +/- 46 vs 39 +/- 15 days, P = 0.05). The TPLDN group had a significantly smaller surgical incision (8.2 +/- 0.6 vs 5.5 +/- 0.4 cm, P %26lt; 0.001) and higher scar satisfaction score (7.8 +/- 1.5 vs 8.6 +/- 1.3, P = 0.02) than the HALDN group. No differences were found in the recipient serum creatinine values or in the incidence of delayed graft function. %26lt;br%26gt;Conclusions: In comparing TPLDN and HALDN, there was no significant difference in a majority of the operative and postoperative parameters. TPLDN might be associated with smaller surgical incision, improved cosmetic satisfaction, and equivalent recipient graft function.
- 出版日期2013-5
